The M3™ compact, high-performance, one-touch MRI system is the smallest of M-series and is intended for dedicated imaging of mice. The M3 enables to generate high-resolution 3D anatomical, functional and molecular images with a “bore” size optimized for mice. The M3’s small bore correlates to a smaller total size (footprint), lighter weight, and more affordable cost. The system can be uniquely placed behind the bio-containment barrier for in vivo imaging. In addition to its comprehensive suite of applications for mouse phenotyping, Ram development in cooperation with Aspect Imaging’s LumiQuant™ package for generation of 3D tomographic quantification of luminescence and co-registration with compact MR is optimized for use on the M3 platform.